Infertility can be a challenge for couples who are trying to have a child. Even with the help of modern diagnostic tools, couples may not be able to get a definite diagnosis. In vitro fertilization (IVF) may be used to treat this condition. Here is more information about the causes of IVF failure and how IVF works:
Causes of IVF Failure
Knowing why IVF may not work can assist people to prepare adequately for their infertility journey. Poor embryo quality is one of the most frequent causes attributed to chromosomal abnormalities or developmental issues. Poor embryo quality may occur due to advanced maternal age since the quality of eggs decreases over time. Implantation failure may occur if the uterine lining is unsuitable due to factors such as a thin endometrial lining, fibroids, or immune issues.
Poor ovarian response is another cause of IVF failure. This is where professionals retrieve fewer eggs because of low levels of ovarian reserve, common in older women or those with conditions such as PCOS. Sperm issues like poor motility or DNA fragmentation can also affect embryo quality and implantation rates in males. IVF’s success can depend on the age of the individuals involved. Not only does the quality of the eggs deteriorate with age, but the receptiveness of the uterus can also be affected. Medical conditions such as endometriosis and autoimmune disorders can also affect the success rate of IVF.
Smoking, obesity, stress, and other lifestyle issues also impact fertility and IVF success rates. Hormonal abnormalities like thyroid disorders or hyperprolactinemia also interfere with the processes necessary for conception. Factors that can improve success rates include leading healthier lifestyles, managing existing health conditions, and consulting with professionals.
IVF and Unexplained Infertility
IVF is a procedure that aims at enhancing every phase of conception, from the union of sperm and egg to the implantation of the embryo. In cases of unexplained infertility, IVF provides a controlled setting that eliminates many of the factors that could prevent conception. Ovarian stimulating agents like gonadotropins are employed to confirm that several mature eggs are produced for collection. This increases the likelihood of getting good eggs even though some are inherently less fertile.
After the eggs have reached maturity, professionals retrieve them through transvaginal ultrasound aspiration. This procedure helps collect eggs directly from the ovaries, bypassing issues with tubal transport. Following retrieval, the eggs are then fertilized with sperm in a process that takes place in a laboratory. Two primary fertilization techniques are used during this stage. In traditional IVF, sperm and eggs are put in a petri dish to facilitate natural conception. In intracytoplasmic sperm injection (ICSI), a single sperm is placed directly into an egg, a procedure that is common when there may be a problem with the sperm.
Professionals monitor the fertilized eggs, now embryos, for several days in a specific culture medium. They monitor their growth and choose the best embryos to transfer. The medical experts place the best-quality embryos into the uterus through a thin tube known as a catheter. The aim is to deposit the embryo in the part of the endometrium that is most favorable for implantation. Following the transfer, the patient takes hormonal drugs such as progesterone to enhance the development of the uterine lining and facilitate implantation.
Work With a Fertility Specialist
IVF offers a modern treatment solution for unexplained infertility. For couples who have been trying to conceive for around a year with no success, in vitro fertilization provides a safe treatment option. If you are facing the issue of unexplained infertility, seek help from a fertility doctor. Discuss the treatment options and start your journey today.
Leave a Reply